Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | UGCG | Q16739 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435127 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL1514267 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| Lactic Acid SCHEMBL427894 | 0.92 | FAAH (0.50) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL10723388 | 0.89 | FAAH (0.58) | ALDH1A1LMNAHTTMEN1KMT2A | |
| SCHEMBL144502 | 0.87 | ALDH1A1 (0.43) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL5673619 | 0.83 | FAAH (0.64) | ALDH1A1LMNAHTTFAAHTP53 | |
| Lactic Acid SCHEMBL344500 | 0.82 | FAAH (0.45) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 | |
| SCHEMBL718238 | 0.81 | FAAH (0.57) | ALDH1A1SMN1; SMN2FAAHTP53CNR1 | |
| SCHEMBL29245563 | 0.81 | FAAH (0.57) | ALDH1A1SMN1; SMN2FAAHTP53CNR1 | |
| SCHEMBL14166869 | 0.79 | ALDH1A1 (0.52) | ALDH1A1LMNAHTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757560-B1 | OPHTHALMIC COMPOSITIONS COMPRISING AMIDOAMINES | ALCON LAB INC (US) | 1999-12-22 | — | — | EP | disclosed |
| EP-0757560-A1 | USE OF AMIDOAMINES IN OPHTHALMIC COMPOSITIONS | ALCON LABORATORIES, INC. (US) | 1997-02-12 | — | — | EP | disclosed |
| US-5573726-A | DISINFECTING CONTACT LENSES | ALCON LABORATORIES, INC. (US) | 1996-11-12 | — | — | US | disclosed |
| WO-1996026747-A2 | USE OF AMIDOAMINES IN OPHTHALMIC COMPOSITIONS | ALCON LABORATORIES, INC. (US) | 1996-09-06 | — | — | WO | disclosed |