Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | UGCG | Q16739 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435136 | 0.92 | ALDH1A1 (0.54) | FAAHMEN1KMT2AMAPK1TP53 | |
| SCHEMBL1514267 | 0.92 | ALDH1A1 (0.54) | FAAHMEN1KMT2AMAPK1TP53 | |
| SCHEMBL8435127 | 0.92 | ALDH1A1 (0.54) | FAAHMEN1KMT2AMAPK1TP53 | |
| Lactic Acid SCHEMBL344500 | 0.90 | FAAH (0.45) | FAAHMEN1KMT2AMAPK1TP53 | |
| SCHEMBL144502 | 0.83 | ALDH1A1 (0.43) | FAAHMEN1KMT2AMAPK1TP53 | |
| SCHEMBL10723388 | 0.82 | FAAH (0.58) | FAAHMEN1KMT2AMAPK1MAPT | |
| SCHEMBL5673619 | 0.79 | FAAH (0.64) | FAAHTP53NFKB1LMNAALDH1A1 | |
| Lactic Acid SCHEMBL6314994 | 0.76 | ALDH1A1 (0.53) | MEN1KMT2AMAPK1TP53CYP3A4 | |
| SCHEMBL14166869 | 0.76 | ALDH1A1 (0.52) | FAAHMEN1KMT2AMAPK1TP53 | |
| SCHEMBL718238 | 0.75 | FAAH (0.57) | FAAHTP53SMN1; SMN2ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118614496-A | Agricultural and forestry flight protection auxiliary agent, preparation method and application | 黑龙江省森林保护研究所 | 2024-09-10 | — | — | CN | claimed |
| CN-117362560-A | Modified phenolic resin and preparation method thereof | 山东永创材料科技有限公司 | 2024-01-09 | — | — | CN | claimed |
| EP-2393469-B1 | Process of treating hair | RHODIA OPERATIONS (FR) | 2016-10-12 | — | — | EP | claimed |
| US-20120021025-A1 | AQUEOUS COMPOSITION SUITABLE AS SHAMPOO | RHODIA OPERATIONS (FR) | 2012-01-26 | — | — | US | claimed |
| WO-2010089228-A9 | AQUEOUS COMPOSITION SUITABLE AS SHAMPOO | RHODIA OPERATIONS (FR) | 2011-04-21 | — | — | WO | claimed |
| WO-2010089228-A1 | AQUEOUS COMPOSITION SUITABLE AS SHAMPOO | RHODIA OPERATIONS (FR) | 2010-08-12 | — | — | WO | claimed |
| EP-2216010-A1 | Aqueous composition suitable as shampoo | Rhodia Opérations (FR) | 2010-08-11 | — | — | EP | claimed |
| US-20080113892-A1 | Antimicrobial wash formulations including amidoamine-based cationic surfactants | SILVER POINT FINANCE, LLC, AS COLLATERAL AGENT | 2008-05-15 | — | — | US | claimed |
| US-20050020475-A1 | Fabric softener system and method for use in clothes dryer | OGDEN & COMPANY, INC. | 2005-01-27 | — | — | US | claimed |
| WO-2003087465-A1 | FABRIC SOFTENER SYSTEM AND METHOD FOR USE IN CLOTHES DRYER | OGDEN & COMPANY, INC. (US) | 2003-10-23 | — | — | WO | claimed |
| US-20030188450-A1 | Fabric softener system and method for use in clothes dryer | OGDEN & COMPANY, INC. | 2003-10-09 | — | — | US | claimed |
| US-20020155962-A1 | Nonaqueous hair styling composition and method of use | ANDREW JERGENS COMPANY, THE | 2002-10-24 | — | — | US | claimed |
| US-12527733-B2 | Fragrance compositions | ELC MANAGEMENT LLC (US) | 2026-01-20 | — | — | US | disclosed |
| CN-118614496-A | Agricultural and forestry flight protection auxiliary agent, preparation method and application | 黑龙江省森林保护研究所 | 2024-09-10 | — | — | CN | disclosed |
| EP-4384137-A1 | FRAGRANCE COMPOSITIONS | ELC Management LLC (US) | 2024-06-19 | — | — | EP | disclosed |
| CN-117940102-A | Fragrance composition | ELC管理有限责任公司 | 2024-04-26 | — | — | CN | disclosed |
| WO-2001007009-A1 | LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE | PERICOR SCIENCE, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| EP-1011609-A4 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORP (US) | 2000-08-16 | — | — | EP | disclosed |
| EP-1011609-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MedLogic Global Corporation (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998050005-A1 | COMPOSITIONS FOR COSMETIC APPLICATIONS | MEDLOGIC GLOBAL CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12527733-B2 | Fragrance compositions | CUTA, IL36G, TAS2R40 | FAAH 64/4885MEN1 4864/4885KMT2A 4603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.