Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | UGCG | Q16739 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144502 | 0.94 | ALDH1A1 (0.43) | FAAHMEN1KMT2AMAPK1TP53 | |
| Lactic Acid SCHEMBL427894 | 0.90 | FAAH (0.50) | FAAHMEN1KMT2AMAPK1TP53 | |
| SCHEMBL8435136 | 0.82 | ALDH1A1 (0.54) | FAAHMEN1KMT2AMAPK1TP53 | |
| SCHEMBL8435127 | 0.82 | ALDH1A1 (0.54) | FAAHMEN1KMT2AMAPK1TP53 | |
| SCHEMBL1514267 | 0.82 | ALDH1A1 (0.54) | FAAHMEN1KMT2AMAPK1TP53 | |
| SCHEMBL2769843 | 0.81 | LMNA (0.42) | FAAHMEN1KMT2AMAPK1TP53 | |
| Lactic Acid SCHEMBL29975332 | 0.80 | GNAI3 (0.41) | FAAHMEN1KMT2AMAPK1TP53 | |
| SCHEMBL2119441 | 0.76 | PLA2G10 (0.35) | FAAHMEN1KMT2AMAPK1TP53 | |
| Lactic Acid SCHEMBL28561710 | 0.75 | ALDH1A1 (0.51) | MEN1KMT2ATP53LMNASMN1; SMN2 | |
| SCHEMBL5673619 | 0.75 | FAAH (0.64) | FAAHTP53NFKB1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456299-A | Preparation method and application of polyacrylic acid thickening agent | 国科温州研究院(温州生物材料与工程研究所) | 2022-05-10 | — | — | CN | claimed |
| CN-108213766-B | Special soldering paste for aluminum product welding and preparation method and use method thereof | 中山翰华锡业有限公司 | 2020-04-28 | — | — | CN | claimed |
| US-20200078273-A1 | METHOD AND APPARATUS FOR REMOVAL OF CONTAMINANTS FROM SURFACES | MCKINNON DANE MICHAEL J (US) | 2020-03-12 | — | — | US | claimed |
| EP-2797599-B9 | METHOD AND IMPROVED PHARMACEUTICAL COMPOSITION FOR ENHANCING TRANSDERMAL DELIVERY OF PDE-5 INHIBITOR | TRITECH BIOPHARMACEUTICALS CO LTD (TW) | 2019-01-23 | — | — | EP | claimed |
| EP-2797599-B1 | METHOD AND IMPROVED PHARMACEUTICAL COMPOSITION FOR ENHANCING TRANSDERMAL DELIVERY OF PDE-5 INHIBITOR | TRITECH BIOPHARMACEUTICALS CO LTD (TW) | 2018-09-12 | — | — | EP | claimed |
| EP-3082740-A1 | SKIN CLEANSING COMPOSITION WITH A DEPOSITION COMPONENT | The Dial Corporation (US) | 2016-10-26 | — | — | EP | claimed |
| US-9427471-B2 | Method and improved pharmaceutical composition for enhancing transdermal delivery of PDE-5 inhibitor | Tritech Biopharmaceuticals Co., Ltd. (TW) | 2016-08-30 | — | — | US | claimed |
| US-9232790-B2 | Antimicrobial cleansing compositions | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2016-01-12 | — | — | US | claimed |
| WO-2015095001-A1 | SKIN CLEANSING COMPOSITION WITH A DEPOSITION COMPONENT | THE DIAL CORPORATION (US) | 2015-06-25 | — | — | WO | claimed |
| US-20150164919-A1 | SKIN CLEANSING COMPOSITION WITH A DEPOSITION COMPONENT | THE DIAL CORPORATION (US) | 2015-06-18 | — | — | US | claimed |
| WO-2003078558-A1 | CLEANSING COMPOSITIONS WITH MILK PROTEIN AND AROMATHERAPY | PLAYTEX PRODUCTS, INC. (US) | 2003-09-25 | — | — | WO | claimed |
| WO-2003063807-A1 | DRY CLEANSING WIPE WITH IMPROVED RINSIBILITY | PLAYTEX PRODUCTS, INC. (US) | 2003-08-07 | — | — | WO | claimed |
| US-20030143263-A1 | Dry cleansing wipe with improved rinsibility | PLAYTEX PRODUCTS, INC. | 2003-07-31 | — | — | US | claimed |
| US-20020177535-A1 | Cleansing compositions with milk protein and aromatherapy | PLAYTEX PRODUCTS, INC. | 2002-11-28 | — | — | US | claimed |
| US-20020151446-A1 | Mild foaming cleanser composition | PLAYTEX PRODUCTS, INC. | 2002-10-17 | — | — | US | claimed |
| WO-2002062936-A1 | MILD FOAMING CLEANSER COMPOSITION | PLAYTEX PRODUCTS, INC. (US) | 2002-08-15 | — | — | WO | claimed |
| US-6120644-A | Tissue containing cationic amidoamine compounds | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2000-09-19 | — | — | US | claimed |
| US-6026822-A | Head bathing system | SAGE PRODUCTS, INC. (US) | 2000-02-22 | — | — | US | claimed |
| EP-0934444-A1 | TISSUE PAPER CONTAINING CATIONIC AMIDOAMINE COMPOUNDS | Kimberly-Clark Worldwide, Inc. (US) | 1999-08-11 | — | — | EP | claimed |
| WO-1998019010-A1 | TISSUE PAPER CONTAINING CATIONIC AMIDOAMINE COMPOUNDS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1998-05-07 | — | — | WO | claimed |