Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118610 | 0.93 | MAOA (0.40) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9728223 | 0.90 | DPP8 (0.46) | TDP1DPP8DPP9 | |
| SCHEMBL9119637 | 0.89 | DPP8 (0.45) | ALDH1A1MAPTHPGDRAB9ADPP8 | |
| SCHEMBL9040592 | 0.87 | ALDH1A1 (0.41) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8434820 | 0.87 | TDP1 (0.43) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9040433 | 0.87 | ALDH1A1 (0.41) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9120984 | 0.87 | OPRK1 (0.39) | TDP1ATMALDH1A1DPP8DPP9 | |
| SCHEMBL8435146 | 0.86 | ALDH1A1 (0.39) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8521258 | 0.86 | MAPT (0.39) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8521254 | 0.86 | MAPT (0.39) | TDP1ATMALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126587-B1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMA (JP) | 1995-04-19 | — | — | EP | disclosed |
| US-5122604-A | 2-(2-Carbonyl-substituted pyrrolidin-4-yl)carbapenems and -penems; microbiocides | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| US-4933333-A | β-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0126587-A1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-11-28 | — | — | EP | disclosed |