Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431821 | 0.79 | MTNR1A (0.59) | HTR5ACYP2A6MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL8882742 | 0.78 | MTNR1A (0.58) | HTR5ACYP2A6MTNR1AMTNR1B | |
| SCHEMBL8435762 | 0.78 | HTR5A (0.54) | HTR5ACYP2A6MTNR1AMTNR1B | |
| SCHEMBL8431855 | 0.77 | HTR1D (0.48) | HTR5ACYP2A6MTNR1AMTNR1BEPHX1 | |
| SCHEMBL8431972 | 0.75 | HTR1A (0.53) | HTR5ACYP2A6MTNR1A | |
| SCHEMBL8591649 | 0.75 | CYP2A6 (0.50) | HTR5ACYP2A6MTNR1AMTNR1B | |
| SCHEMBL8432503 | 0.74 | HTR1D (0.52) | HTR5ACYP2A6MTNR1AMTNR1BEPHX1 | |
| SCHEMBL8434421 | 0.73 | HTR1A (0.56) | HTR5ACYP2A6MTNR1A | |
| SCHEMBL4324624 | 0.72 | CYP2A6 (0.75) | HTR5ACYP2A6EPHX1SMN1; SMN2 | |
| SCHEMBL8586692 | 0.72 | HTR2C (0.49) | HTR5ACYP2A6MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721938-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-08 | — | — | EP | disclosed |
| EP-0721938-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |