Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431972 | 0.91 | HTR1A (0.53) | HTR5AMTNR1ACYP2A6HTR1AHTR1D | |
| SCHEMBL8431821 | 0.89 | MTNR1A (0.59) | HTR5AMTNR1ACYP2A6HTR1AHTR1D | |
| SCHEMBL8434421 | 0.88 | HTR1A (0.56) | HTR5AMTNR1ACYP2A6HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL8882742 | 0.88 | MTNR1A (0.58) | HTR5AMTNR1ACYP2A6HTR1AHTR1D | |
| SCHEMBL8037709 | 0.80 | MTNR1A (0.56) | HTR5AMTNR1ACYP2A6HTR1AHTR1D | |
| SCHEMBL9751556 | 0.79 | CA2 (0.56) | HTR5AMTNR1ACYP2A6HTR1DMTNR1B | |
| SCHEMBL8591649 | 0.78 | CYP2A6 (0.50) | HTR5AMTNR1ACYP2A6MTNR1BCA2 | |
| SCHEMBL8436358 | 0.78 | HTR5A (0.51) | HTR5AMTNR1ACYP2A6MTNR1B | |
| Hydrochloric Acid SCHEMBL9751543 | 0.78 | CA2 (0.55) | HTR5AMTNR1ACYP2A6HTR1DMTNR1B | |
| SCHEMBL8586692 | 0.76 | HTR2C (0.49) | HTR5AMTNR1ACYP2A6HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721938-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1999-12-08 | — | — | EP | disclosed |
| EP-0721938-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |