Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GGT1 | P19440 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28908111 | 0.85 | KDM4E (0.45) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Diaspirin SCHEMBL40799 | 0.85 | KDM4E (0.75) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL844727 | 0.85 | KDM4E (0.70) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Diaspirin SCHEMBL30735506 | 0.85 | KDM4E (0.75) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL6692076 | 0.84 | MAPK1 (0.58) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL11436828 | 0.84 | KDM4E (0.45) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL6691255 | 0.84 | TOP2A (0.45) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL8436639 | 0.83 | KDM4E (0.63) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL10879664 | 0.82 | ALDH1A1 (0.49) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL10632959 | 0.82 | KDM4E (0.43) | KDM4EKMT2AMEN1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793478-A4 | ORAL COMPOSITIONS | PROCTER & GAMBLE (US) | 2005-10-12 | — | — | EP | disclosed |
| EP-0801555-B1 | ORAL COMPOSITIONS CONTAINING DIMETHICONE COPOLYOLS | PROCTER & GAMBLE (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0863742-B1 | GRANULAR POWDERS CONTAINING SILICONE OIL | PROCTER & GAMBLE (US) | 2003-10-08 | — | — | EP | disclosed |
| US-20030099603-A1 | Polybutene containing denture cleanser compositions | RAJAIAH JAYANTH (US) | 2003-05-29 | — | — | US | disclosed |
| US-6491896-B1 | ANTICARIES PARTICLES OR TABLETS COMPRISING ADDITION POLYMERS, BLEACHES AND EFFERVESCENCE GENERATORS | THE PROCTOR & GAMBLE COMPANY | 2002-12-10 | — | — | US | disclosed |
| WO-2002074263-A2 | POLYBUTENE CONTAINING DENTURE CLEANSER COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2002-09-26 | — | — | WO | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6294154-B1 | PROLONGED, RESIDUAL ANTIMICROBIAL AND/OR FLAVOR IMPACT EFFECT. TOOTHPASTE, POWDER, LIQUID DENTIFRICE, MOUTHWASH, DENTURE CLEANSER, CHEWING GUM OR CANDY | PROCTER AND GAMBLE COMPANY | 2001-09-25 | — | — | US | disclosed |
| US-6153567-A | CLEANING COMPOUNDS; DENTURES | THE PROCTER & GAMBLE COMPANY (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0150532-A1 | Peroxygen bleach activators and bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 1985-08-07 | — | — | EP | disclosed |
| US-4486327-A | FOR PEROXYGEN COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1984-12-04 | — | — | US | disclosed |
| US-4483778-A | Peroxygen bleach activators and bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 1984-11-20 | — | — | US | disclosed |
| US-4374747-A | Bleach products | LEVER BROTHERS COMPANY (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0018678-B1 | BLEACH PRODUCTS | UNILEVER N.V. (NL) | 1982-04-07 | — | — | EP | disclosed |
| EP-0018678-A1 | Bleach products | UNILEVER N.V. (NL) | 1980-11-12 | — | — | EP | disclosed |
| US-4130392-A | Bleaching process | THE PROCTER & GAMBLE COMPANY (US) | 1978-12-19 | — | — | US | disclosed |
| US-4079016-A | SOLID POLYLACTONE DERIVED FROM AN A-HYDROXYACRYLIC ACID POLYMER | SOLVAY & CIE. (BE) | 1978-03-14 | — | — | US | disclosed |
| US-4017411-A | Bleaching articles | THE PROCTER & GAMBLE COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3945936-A | POLYURETHANE POROUS POUCH RELEASABLY CONTAINING PEROXYGEN BLEACH, CLOTHES DRYER | THE PROCTER & GAMBLE COMPANY (US) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030099603-A1 | Polybutene containing denture cleanser compositions | TAS2R8, TAS2R40, TAS2R42 | KDM4E 336/4885KMT2A 888/4885MEN1 2836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.