Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GGT1 | P19440 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844727 | 0.85 | KDM4E (0.70) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Diaspirin SCHEMBL40799 | 0.85 | KDM4E (0.75) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Diaspirin SCHEMBL30735506 | 0.85 | KDM4E (0.75) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL8436639 | 0.83 | KDM4E (0.63) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL25946877 | 0.82 | KDM4E (0.67) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL2763226 | 0.81 | KDM4E (0.71) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL6129343 | 0.81 | KDM4E (0.61) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL13006825 | 0.81 | KDM4E (0.72) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL3765406 | 0.81 | KDM4E (0.81) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL7529982 | 0.81 | KDM4E (0.61) | KDM4EKMT2AMEN1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572907-B2 | Methods and compounds for polynucleotide synthesis | AGILENT TECHNOLOGIES, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| EP-1717242-A1 | Polynucleotide synthesis | Agilent Technologies, Inc. (US) | 2006-11-02 | — | — | EP | disclosed |
| US-20060247430-A1 | Methods and compounds for polynucleotide synthesis | AGILENT TECHNOLOGIES, INC. | 2006-11-02 | — | — | US | disclosed |
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247430-A1 | Methods and compounds for polynucleotide synthesis | POLN, POLRMT, POLM | KDM4E 4662/4885KMT2A 3846/4885MEN1 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.