Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436802 | 0.84 | ADAM17 (0.49) | SMN1; SMN2ALDH1A1MAPTMAPK1 | |
| SCHEMBL5759290 | 0.73 | ADAM17 (0.50) | SMN1; SMN2ALDH1A1MAPTALOX5EPHX2 | |
| SCHEMBL8433487 | 0.73 | MMP1 (0.43) | — | |
| SCHEMBL8433497 | 0.73 | MMP1 (0.43) | — | |
| SCHEMBL7544973 | 0.68 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9422610 | 0.67 | ALOX5 (0.63) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8521842 | 0.67 | ADAM17 (0.58) | — | |
| SCHEMBL6379495 | 0.67 | MMP1 (0.65) | — | |
| SCHEMBL5760549 | 0.67 | ALDH1A1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5760724 | 0.67 | MMP1 (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960098-A1 | ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-12-01 | — | — | EP | disclosed |
| WO-1998034918-A1 | ARYLSULFONYL HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-08-13 | — | — | WO | disclosed |