Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482961 | 0.88 | ALDH1A1 (0.40) | ALDH1A1KDM4EKMT2AGAATP53 | |
| SCHEMBL28463231 | 0.84 | L3MBTL1 (0.33) | ALDH1A1KDM4ELMNA | |
| SCHEMBL28519204 | 0.82 | L3MBTL1 (0.32) | — | |
| SCHEMBL20504314 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM4ERXFP1KMT2AGAA | |
| SCHEMBL27970356 | 0.76 | L3MBTL1 (0.31) | — | |
| SCHEMBL4434695 | 0.74 | L3MBTL1 (0.33) | GAACA1CA2 | |
| SCHEMBL7646127 | 0.74 | SIGMAR1 (0.34) | ALDH1A1GAALMNA | |
| SCHEMBL20504316 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4ERXFP1KMT2AGAA | |
| SCHEMBL12801182 | 0.74 | KDM4E (0.47) | ALDH1A1KDM4EGAACYP2C19LMNA | |
| Alcohol SCHEMBL7566185 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4ERXFP1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4423103-A1 | DNA-ENCODED AND AFFINITY-TAGGED MASKED-WARHEAD COMPOUNDS AND USE THEREOF IN ASSEMBLING LIBRARIES OF SMALL MOLECULES ENABLED FOR LATE-STAGE PURIFICATION AND MULTIPLEXED SCREENING OF COVALENT LIGANDS | Maianti, Juan Pablo (US) | 2024-09-04 | — | — | EP | disclosed |
| US-20230407293-A1 | DNA-ENCODED AND AFFINITY-TAGGED MASKED-WARHEAD COMPOUNDS AND USE THEREOF IN ASSEMBLING LIBRARIES OF SMALL MOLECULES ENABLED FOR LATE-STAGE PURIFICATION AND MULTIPLEXED SCREENING OF COVALENT LIGANDS | MAIANTI JUAN PABLO (US) | 2023-12-21 | — | — | US | disclosed |
| WO-2023077001-A1 | DNA-ENCODED AND AFFINITY-TAGGED MASKED-WARHEAD COMPOUNDS AND USE THEREOF IN ASSEMBLING LIBRARIES OF SMALL MOLECULES ENABLED FOR LATE-STAGE PURIFICATION AND MULTIPLEXED SCREENING OF COVALENT LIGANDS | MAIANTI JUAN PABLO (US) | 2023-05-04 | — | — | WO | disclosed |
| CN-101754990-A | Water-dispersible polyisocyanates | BASF SE | 2010-06-23 | — | — | CN | disclosed |
| US-5885788-A | CONDUCTING THE MEASUREMENT OF CHOLESTEROL IN THE PRESENCE OF AN AMPHOTERIC SURFACTANT AND AN ALIPHATIC AMINE CONTAINING CARBOXYL GROUPS(S) OR SULFONIC ACID GROUP(S) | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5814472-A | REACTING LIVING SAMPLE WITH CHOLESTEROL OXIDASE OR CHOLESTEROL DEHYDROGENASE IN PRESENCE OF AMPHOTERIC SURFACTANT AND CYCLODEXTRIN | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-29 | — | — | US | disclosed |
| US-5790627-A | Method and apparatus for observing a specimen using an X-ray microscope | RESEARCH DEVELOPMENT CORP. (JP) | 1998-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230407293-A1 | DNA-ENCODED AND AFFINITY-TAGGED MASKED-WARHEAD COMPOUNDS AND USE THEREOF IN ASSEMBLING LIBRARIES OF SMALL MOLECULES ENABLED FOR LATE-STAGE PURIFICATION AND MULTIPLEXED SCREENING OF COVALENT LIGANDS | DNA2, WRN, DCLRE1A | ALDH1A1 2197/4885KDM4E 2219/4885RXFP1 4816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.