SCHEMBL3482961

SCHEMBL3482961

CCS(=O)(=O)ON1CCN(CCO)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 1/20 0.38
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
KMT2A Q03164 3/20 0.33
TP53 P04637 2/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33
CYP2C19 P33261 2/20 0.33
MEN1 O00255 2/20 0.33
NPC1 O15118 1/20 0.33
GAA P10253 1/20 0.33
RAB9A P51151 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
HSD11B1 P28845 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8437271 0.88 ALDH1A1 (0.37) ALDH1A1KDM4ECHRM2CHRM1KMT2A
SCHEMBL510149 0.80 HSD11B1 (0.35) ALDH1A1KMT2ALMNAHSD11B1POLB
SCHEMBL28119037 0.76
SCHEMBL9405550 0.73 GAA (0.30) GAA
SCHEMBL28122577 0.73 GAA (0.31) KMT2AGAA
Alcohol SCHEMBL7566185 0.73 ALDH1A1 (0.41) ALDH1A1KDM4ECHRM2CHRM1KMT2A
SCHEMBL7566192 0.73 ALDH1A1 (0.39) ALDH1A1KDM4ECHRM2CHRM1KMT2A
SCHEMBL7650739 0.73 SIGMAR1 (0.37) ALDH1A1KMT2ALMNAHTTMEN1
SCHEMBL27545411 0.73 ALDH1A1 (0.36) ALDH1A1KDM4ECHRM2CHRM1KMT2A
Sulfuric Acid SCHEMBL9359044 0.72 ALDH1A1 (0.44) ALDH1A1KDM4ECHRM2CHRM1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2010510819-A 2010-04-08 JP claimed
US-20100080834-A1 Film Material With Antimicrobial And/Or Odor-Absorbing Coating and Sanitary Article NUOVA PANSAC S.P.A. (IT) 2010-04-01 US claimed
EP-2084323-A2 FILM MATERIAL WITH ANTIMICROBIAL AND/OR ODOR-ABSORBING COATING AND SANITARY ARTICLE Nuova Pansac S.p.A. (IT) 2009-08-05 EP claimed
WO-2008062291-A2 FILM MATERIAL WITH ANTIMICROBIAL AND/OR ODOR-ABSORBING COATING AND SANITARY ARTICLE NUOVA PANSAC S.P.A. (IT) 2008-05-29 WO claimed
EP-3590944-B1 AZETIDINE DERIVATIVE CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) 2022-09-14 EP disclosed
EP-4021474-A2 RAPID ISOLATION AND COLLECTION OF MICROBIAL RNA FROM A BIOLOGICAL SPECIMEN Contamination Source Identification LLC (US) 2022-07-06 EP disclosed
US-11014943-B2 Azetidine derivative CHIA TAI TIANQING PHARMACEUTICAL GROUP GO., LTD. (CN) 2021-05-25 US disclosed
WO-2021042135-A2 RAPID ISOLATION AND COLLECTION OF MICROBIAL RNA FROM A BIOLOGICAL SPECIMEN CONTAMINATION SOURCE IDENTIFICATION LLC (US) 2021-03-04 WO disclosed
EP-3489219-B1 THERAPEUTIC AGENT FOR GLAUCOMA TOA EIYO LTD (JP) 2020-12-16 EP disclosed
CN-111867589-A Compounds for treating tumors in a subject and uses thereof 默克专利股份有限公司 2020-10-30 CN disclosed
US-10682323-B2 Therapeutic agent for glaucoma TOA EIYO LTD. (JP) 2020-06-16 US disclosed
US-20200115392-A1 AZETIDINE DERIVATIVE CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2020-04-16 US disclosed
US-20040091874-A1 Sensor chip for nucleic acid selection NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 2004-05-13 US disclosed
US-5958978-A ADMINISTERING 2-(2,6-DICHLORO-4-HYDROXYANILINO)PHENYLACETIC ACID KABUSHIKI KAISHA YAKULT HONSHA (JP) 1999-09-28 US disclosed
US-5885788-A CONDUCTING THE MEASUREMENT OF CHOLESTEROL IN THE PRESENCE OF AN AMPHOTERIC SURFACTANT AND AN ALIPHATIC AMINE CONTAINING CARBOXYL GROUPS(S) OR SULFONIC ACID GROUP(S) WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1999-03-23 US disclosed
US-5814472-A REACTING LIVING SAMPLE WITH CHOLESTEROL OXIDASE OR CHOLESTEROL DEHYDROGENASE IN PRESENCE OF AMPHOTERIC SURFACTANT AND CYCLODEXTRIN WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1998-09-29 US disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed
US-5783570-A COATINGS TOYO BOSEKI KABUSHIKI KAISHA (JP) 1998-07-21 US disclosed
US-5382530-A USING COMPETITIVE BINDING TECHNOGENETICS S.R.L. (IT) 1995-01-17 US disclosed
EP-0565949-A2 Method for the quantitative determination of a free form of substances present in biological fluids TECHNOGENETICS S.r.l. (IT) 1993-10-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10682323-B2 Therapeutic agent for glaucoma GUCY1A2, PDE3A, GUCY1B1 ALDH1A1 1419/4885KDM4E 3942/4885CHRM2 1256/4885
US-11014943-B2 Azetidine derivative BCL9, MCL1, BCL9L ALDH1A1 727/4885KDM4E 1404/4885CHRM2 1755/4885
US-20200115392-A1 AZETIDINE DERIVATIVE BCL9, MCL1, BCL9L ALDH1A1 727/4885KDM4E 1404/4885CHRM2 1755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.