Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540193 | 1.00 | CTSK (0.37) | CTSKCTSBCTSSEPHX2DPP8 | |
| SCHEMBL8574927 | 0.90 | CTSK (0.46) | CTSKCTSBCTSSLMNAKDM4E | |
| SCHEMBL8438142 | 0.89 | HSD11B1 (0.41) | EPHX2DPP8DPP9HSD11B1LMNA | |
| SCHEMBL8438145 | 0.89 | HSD11B1 (0.41) | EPHX2DPP8DPP9HSD11B1LMNA | |
| SCHEMBL8438547 | 0.89 | HSD11B1 (0.41) | EPHX2DPP8DPP9HSD11B1LMNA | |
| SCHEMBL9574306 | 0.88 | ALDH1A1 (0.36) | EPHX2DPP8DPP9HSD11B1LMNA | |
| SCHEMBL8542239 | 0.88 | EPHX2 (0.35) | EPHX2DPP8DPP9MMP2ANPEP | |
| SCHEMBL8541702 | 0.88 | EPHX2 (0.35) | EPHX2DPP8DPP9MMP2ANPEP | |
| SCHEMBL9574282 | 0.85 | ALDH1A1 (0.36) | EPHX2DPP8DPP9LMNASIGMAR1 | |
| SCHEMBL9574544 | 0.85 | ALDH1A1 (0.36) | EPHX2DPP8DPP9LMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |