Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472876 | 0.82 | CHRNA3 (0.59) | ALOX5APFEN1CHRNB2CHRNA4GPR119 | |
| SCHEMBL6588716 | 0.82 | CHRNA3 (0.59) | ALOX5APFEN1CHRNB2CHRNA4GPR119 | |
| SCHEMBL388491 | 0.82 | KDM4E (0.47) | ALOX5APFEN1GPR119 | |
| SCHEMBL17878836 | 0.80 | SSTR4 (0.49) | ALOX5APFEN1GPR119 | |
| SCHEMBL27462042 | 0.79 | GPR119 (0.48) | ALOX5APFEN1TSHRGPR119 | |
| SCHEMBL8439210 | 0.78 | ALOX5AP (0.39) | ALOX5APFEN1LMNAKMT2ATSHR | |
| SCHEMBL7414793 | 0.77 | GPR119 (0.48) | ALOX5APFEN1GPR119 | |
| SCHEMBL7415559 | 0.76 | POLB (0.50) | ALOX5APFEN1CHRNB2CHRNA4GPR119 | |
| SCHEMBL7484779 | 0.76 | POLB (0.50) | ALOX5APFEN1CHRNB2CHRNA4GPR119 | |
| Oxalic Acid SCHEMBL8439350 | 0.76 | CHRNA3 (0.54) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948793-A | 3-pyridyloxymethyl heterocyclic ether compounds useful in controlling neurotransmitter release | ABBOTT LABORATORIES (US) | 1999-09-07 | — | — | US | disclosed |
| US-5914328-A | CONTROL DOPAMINE RELEASE, ACTIVATE CHOLINERGIC CHANNELS | ABBOTT LABORATORIES (US) | 1999-06-22 | — | — | US | disclosed |