Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522389 | 0.84 | POLB (0.44) | POLBMEN1KMT2AATMABCB1 | |
| SCHEMBL8668979 | 0.80 | MEN1 (0.36) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL8670315 | 0.80 | MAPT (0.33) | MEN1KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8438639 | 0.80 | POLB (0.43) | POLBMEN1KMT2AATMABCB1 | |
| SCHEMBL8438828 | 0.80 | KMT2A (0.41) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL8672636 | 0.77 | SMN1; SMN2 (0.37) | POLBMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8442772 | 0.76 | HTR1D (0.41) | MEN1KMT2AATMKDM4ESMN1; SMN2 | |
| SCHEMBL8436458 | 0.76 | MAPT (0.48) | KMT2AABCB1MAPTKDM4EALDH1A1 | |
| SCHEMBL8440207 | 0.75 | NPSR1 (0.36) | MEN1KMT2AATMMAPTKDM4E | |
| SCHEMBL8522391 | 0.74 | POLB (0.45) | POLBMEN1KMT2AATMABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |