Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443199 | 0.86 | TDP1 (0.43) | POLBMAPTTDP1HRH3SMN1; SMN2 | |
| SCHEMBL8439867 | 0.84 | LMNA (0.44) | POLBLMNASMN1; SMN2 | |
| SCHEMBL8438635 | 0.84 | POLB (0.43) | POLBMEN1KMT2AATMMAPT | |
| SCHEMBL8441858 | 0.81 | CYP2D6 (0.44) | POLBMAPTKCNH2HRH3CYP2D6 | |
| SCHEMBL8442148 | 0.80 | KMT2A (0.44) | POLBMEN1KMT2AMAPTKCNH2 | |
| SCHEMBL8441415 | 0.80 | LMNA (0.43) | KDM4ELMNAKCNH2HRH3SMN1; SMN2 | |
| SCHEMBL8672721 | 0.80 | PTGS2 (0.40) | POLBMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8522391 | 0.79 | POLB (0.45) | POLBMEN1KMT2AATMMAPT | |
| SCHEMBL8551375 | 0.78 | KDM4E (0.39) | POLBMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8668966 | 0.76 | SMN1; SMN2 (0.38) | KMT2AMAPTKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916904-A | ANTIULCER | EISAI CO., LTD. (JP) | 1999-06-29 | — | — | US | disclosed |