Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527387 | 0.78 | HRH3 (0.43) | — | |
| SCHEMBL2512584 | 0.76 | TP53 (0.43) | SCN1ASCN2ASCN3AALDH1A1HTT | |
| SCHEMBL4621770 | 0.74 | DHFR (0.43) | ALDH1A1SLC6A3 | |
| SCHEMBL12200810 | 0.72 | GAA (0.41) | LMNAALDH1A1HPGDMAPK1L3MBTL1 | |
| SCHEMBL28423359 | 0.72 | AKR1C3 (0.59) | CYP19A1ALDH1A1L3MBTL1AKR1C3GAA | |
| SCHEMBL7027549 | 0.72 | DRD2 (0.41) | DRD2DRD1DRD3ABCB1LMNA | |
| SCHEMBL2517872 | 0.71 | ALDH1A1 (0.46) | LMNAALDH1A1HPGDHTTGAA | |
| SCHEMBL23038404 | 0.70 | SLC6A3 (0.34) | SLC6A3 | |
| SCHEMBL6498977 | 0.70 | ELANE (0.49) | ABCB1LMNAALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7252078 | 0.69 | AKR1C3 (0.52) | CYP19A1ABCB1ALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960909-A2 | Polymeric compositions | Enichem S.p.A. (IT) | 1999-12-01 | — | — | EP | disclosed |