Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490088 | 0.94 | PSMB1 (0.42) | ELANENPC1MEN1KMT2APOLB | |
| SCHEMBL6501299 | 0.82 | CA4 (0.34) | LTA4HKDM4ETSHRHSD17B10 | |
| SCHEMBL4625144 | 0.75 | KMT2A (0.61) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7935404 | 0.73 | LMNA (0.48) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7027544 | 0.73 | ELANE (0.41) | ELANEMEN1KMT2AALDH1A1ABCB1 | |
| SCHEMBL6503405 | 0.72 | CYP1A2 (0.44) | NPC1KDM4EHPGDRAB9A | |
| Benzophenone SCHEMBL27766299 | 0.71 | ALDH1A1 (0.82) | ELANENPC1MEN1KMT2APOLB | |
| SCHEMBL5471885 | 0.70 | ESR1 (0.49) | ELANENPC1MEN1KMT2APOLB | |
| SCHEMBL4235665 | 0.69 | CYP3A4 (0.50) | MEN1KMT2AALDH1A1LMNATP53 | |
| SCHEMBL6544700 | 0.69 | GAA (0.54) | NPC1MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579328-B2 | Preparation from a sterically hindered nitroxy compound and a diazonium salt of an aromatic amine in the presence of a transition metal catalyst | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-17 | — | — | US | claimed |
| EP-1278733-A1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED ARYLOXYAMINES | Ciba SC Holding AG (CH) | 2003-01-29 | — | — | EP | claimed |
| US-20020007585-A1 | Transition-metal-catalyzed process for the preparation of sterically hindered N-substituted aryloxyamines | CIBA SPECIALTY CHEMICALS CORP. | 2002-01-24 | — | — | US | claimed |
| WO-2001083455-A1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED ARYLOXYAMINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-11-08 | — | — | WO | claimed |
| US-6841668-B2 | Polyoxometalate catalysts for the preparation of sterically hindered N-substituted aryloxyamines | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-01-11 | — | — | US | disclosed |
| US-20030208071-A1 | Polyoxometalate catalysts for the preparation of sterically hindered N-substituted aryloxyamines | CIBA SPECIALTY CHEMICALS CORP. | 2003-11-06 | — | — | US | disclosed |
| US-6579328-B2 | Preparation from a sterically hindered nitroxy compound and a diazonium salt of an aromatic amine in the presence of a transition metal catalyst | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-17 | — | — | US | disclosed |
| EP-1278733-A1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED ARYLOXYAMINES | Ciba SC Holding AG (CH) | 2003-01-29 | — | — | EP | disclosed |
| US-20020007585-A1 | Transition-metal-catalyzed process for the preparation of sterically hindered N-substituted aryloxyamines | CIBA SPECIALTY CHEMICALS CORP. | 2002-01-24 | — | — | US | disclosed |
| WO-2001083455-A1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED ARYLOXYAMINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030208071-A1 | Polyoxometalate catalysts for the preparation of sterically hindered N-substituted aryloxyamines | KMO, PPOX, TAOK1 | ELANE 4667/4885NPC1 4399/4885MEN1 731/4885 |
| US-20020007585-A1 | Transition-metal-catalyzed process for the preparation of sterically hindered N-substituted aryloxyamines | SOD1, NNMT, TYR | ELANE 2227/4885NPC1 3545/4885MEN1 1795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.