Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.42 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853476 | 0.82 | CA2 (0.43) | NPFFR1NPFFR2LIMK1LIMK2POLB | |
| Hydrochloric Acid SCHEMBL7841180 | 0.73 | CYP1A2 (0.41) | NPFFR1NPFFR2RAB9ANPC1KMT2A | |
| SCHEMBL9311052 | 0.71 | KMT2A (0.47) | RAB9AKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL7849002 | 0.71 | POLB (0.46) | POLBRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL7823070 | 0.71 | RAB9A (0.51) | POLBRAB9ANPC1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7839095 | 0.70 | KMT2A (0.46) | RAB9AKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL11142454 | 0.69 | ALDH1A1 (0.71) | POLBRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL7838973 | 0.67 | ALDH1A1 (0.39) | POLBRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL24328063 | 0.67 | NPC1 (0.52) | POLBRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL7848997 | 0.66 | NPFFR1 (0.61) | NPFFR1NPFFR2RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891889-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-04-06 | — | — | US | disclosed |