Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474603 | 0.88 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10THRBTDP1 | |
| SCHEMBL11249852 | 0.86 | — | — | |
| SCHEMBL11617859 | 0.80 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10TDP1TSHR | |
| SCHEMBL6539584 | 0.80 | ALDH1A1 (0.30) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL31135467 | 0.79 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10THRBTDP1 | |
| SCHEMBL7058655 | 0.78 | LMNA (0.39) | ALDH1A1LMNAHSD17B10THRBTDP1 | |
| SCHEMBL16843395 | 0.78 | THRB (0.44) | ALDH1A1LMNAHSD17B10THRBTDP1 | |
| SCHEMBL12955806 | 0.77 | — | — | |
| SCHEMBL12047635 | 0.77 | — | — | |
| SCHEMBL12955873 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115785040-B | Chiral synthesis method of active natural products curcumene and iso Ji Mafu lactone | 中北大学 | 2024-07-02 | — | — | CN | claimed |
| CN-115785040-A | Chiral synthesis method of active natural products curzerene and isogermacrofuryl lactone | 中北大学 | 2023-03-14 | — | — | CN | claimed |
| EP-3830088-A1 | SYNTHESIS OF COELENTERAZINE | International Paper Company (US) | 2021-06-09 | — | — | EP | claimed |
| US-20240239803-A1 | SYNTHESIS OF COELENTERAZINE | INTERNATIONAL PAPER COMPANY | 2024-07-18 | — | — | US | disclosed |
| CN-115785040-B | Chiral synthesis method of active natural products curcumene and iso Ji Mafu lactone | 中北大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-114940644-B | Crystallization method of 2, 7-dimethyl-2, 4, 6-octatriene-1, 8-dialdehyde | 万华化学集团股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| US-20240081675-A1 | BREATH BIOMARKERS OF SARS-COV-2 IN CHILDREN AND METHODS OF USE THEREOF FOR THE DIAGNOSIS AND TREATMENT OF COVID-19 | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2024-03-14 | — | — | US | disclosed |
| US-11903380-B2 | Aqueous composition based on polyoxymethylene dialkyl ethers (POM) and their use for the preservation and/or embalming of the human or animal body | ARKEMA FRANCE (FR) | 2024-02-20 | — | — | US | disclosed |
| CN-115785040-A | Chiral synthesis method of active natural products curzerene and isogermacrofuryl lactone | 中北大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-112638992-B | Dual curable organopolysiloxane composition | 美国陶氏有机硅公司 | 2023-02-10 | — | — | CN | disclosed |
| CN-114940644-A | Crystallization method of 2, 7-dimethyl-2, 4, 6-octatriene-1, 8-dialdehyde | 万华化学集团股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| EP-1059283-B1 | Process for preparing neuraminidase inhibitor ro-64-0796 | HOFFMANN LA ROCHE (CH) | 2003-05-28 | — | — | EP | disclosed |
| US-6437171-B1 | AZIDE-FREE; PREPARING 2-AMINOALCOHOLS FROM 1,2-EPOXIDES AND AN AMINE; PROTECTING THE FREE AMINO GROUP, HYDROXY LEAVING GROUP, DEPROTECTING, REACTING WITH AN AMINE, ACYLATING, DEPROTECTING | HOFFMAN-LA ROCHE INC. | 2002-08-20 | — | — | US | disclosed |
| US-20020095040-A1 | Process for preparing 1,2-diamino compounds | KARPF MARTIN (CH) | 2002-07-18 | — | — | US | disclosed |
| EP-1187798-A1 | PRODUCTION OF OPTICALLY ACTIVE $g(a)-HYDROXYACETALS | Solvias AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001000545-A1 | PRODUCTION OF OPTICALLY ACTIVE α-HYDROXYACETALS | SOLVIAS AG (CH) | 2001-01-04 | — | — | WO | disclosed |
| EP-1059283-A1 | Process for preparing neuraminidase inhibitor ro-64-0796 | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-13 | — | — | EP | disclosed |
| EP-0122479-A1 | 3-Chloro-1,1-dialkoxy-acetones and process for their preparation | Wacker-Chemie GmbH (DE) | 1984-10-24 | — | — | EP | disclosed |
| US-4107159-A | Acetal hydrazones of 2-hydrazino-3H-1,4-benzodiazepine | THE UPJOHN COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4086230-A | 1,5-Dihydro-7-aryl-as-triazine[4,3,-α][1,4]benzodiazepin-1-ols | THE UPJOHN COMPANY (US) | 1978-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020095040-A1 | Process for preparing 1,2-diamino compounds | AOC1, UGT1A1, THPO | ALDH1A1 48/4885LMNA 2657/4885HSD17B10 2158/4885 |
| US-20240239803-A1 | SYNTHESIS OF COELENTERAZINE | ACHE, UROD, DDT | ALDH1A1 313/4885LMNA 4726/4885HSD17B10 1493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.