Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577660 | 0.88 | RECQL (0.36) | DPP8DPP9KCNJ1KCNH2MGLL | |
| SCHEMBL8536750 | 0.86 | KCNJ1 (0.42) | KCNJ1KCNH2HRH2HRH1ALDH1A1 | |
| SCHEMBL8438589 | 0.86 | KCNJ1 (0.42) | KCNJ1KCNH2HRH2HRH1ALDH1A1 | |
| SCHEMBL9728223 | 0.86 | DPP8 (0.46) | DPP8DPP9TDP1 | |
| SCHEMBL8835181 | 0.86 | KCNJ1 (0.37) | DPP8DPP9TDP1KCNJ1KCNH2 | |
| SCHEMBL9040433 | 0.85 | ALDH1A1 (0.41) | TDP1HRH2HRH1ALDH1A1MAPT | |
| SCHEMBL9040592 | 0.85 | ALDH1A1 (0.41) | TDP1HRH2HRH1ALDH1A1MAPT | |
| SCHEMBL9119637 | 0.85 | DPP8 (0.45) | DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL6946646 | 0.85 | DPP8 (0.45) | DPP8DPP9TDP1ALDH1A1MAPT | |
| SCHEMBL8434840 | 0.84 | HRH2 (0.41) | TDP1KCNJ1KCNH2HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5614624-A | THIO SUBSTITUTED, ANTIBIOTICS, CHEMICAL INTERMEDIATES | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5310735-A | Carbapenem derivatives having antibiotic activity, their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 1994-05-10 | — | — | US | disclosed |