Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040433 | 1.00 | ALDH1A1 (0.41) | ALDH1A1HPGDKMT2AMEN1GAA | |
| Trifluoromethanesulfonic Acid SCHEMBL9125753 | 0.92 | CCR5 (0.39) | ALDH1A1HPGDKMT2AMEN1GAA | |
| SCHEMBL9728223 | 0.91 | DPP8 (0.46) | NPBWR1MCHR1TDP1 | |
| SCHEMBL9119637 | 0.90 | DPP8 (0.45) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL8536750 | 0.90 | KCNJ1 (0.42) | ALDH1A1KMT2ASMN1; SMN2ATMHRH2 | |
| Dimethylamine SCHEMBL6943989 | 0.90 | ALDH1A1 (0.41) | ALDH1A1HPGDKMT2AMAPTLMNA | |
| SCHEMBL8438589 | 0.90 | KCNJ1 (0.42) | ALDH1A1KMT2ASMN1; SMN2ATMHRH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL9127836 | 0.89 | CCR5 (0.37) | NPBWR1MCHR1 | |
| SCHEMBL8588093 | 0.89 | PDK1 (0.45) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL8435953 | 0.89 | PDK1 (0.45) | ALDH1A1HPGDKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442497-B1 | Novel beta-lactam compounds and their production | SUMITOMO PHARMA (JP) | 1996-08-14 | — | — | EP | disclosed |
| US-5227376-A | Quaternary ammonium carbapenem antibiotics | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0442497-A1 | Novel beta-lactam compounds and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-21 | — | — | EP | disclosed |