Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728223 | 0.99 | DPP8 (0.46) | DPP8DPP9NPBWR1MCHR1 | |
| SCHEMBL9040592 | 0.90 | ALDH1A1 (0.41) | NPBWR1MCHR1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9040433 | 0.90 | ALDH1A1 (0.41) | NPBWR1MCHR1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9120984 | 0.90 | OPRK1 (0.39) | DPP8DPP9NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL9199817 | 0.89 | TDP1 (0.40) | DPP8DPP9NPC1RAB9AALDH1A1 | |
| SCHEMBL9120876 | 0.89 | ALDH1A1 (0.44) | DPP8DPP9NPC1RAB9AALDH1A1 | |
| SCHEMBL8434820 | 0.88 | TDP1 (0.43) | DPP8DPP9ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8536750 | 0.88 | KCNJ1 (0.42) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8438589 | 0.88 | KCNJ1 (0.42) | ALDH1A1SMN1; SMN2KMT2A | |
| Dimethylamine SCHEMBL6943989 | 0.88 | ALDH1A1 (0.41) | DPP8DPP9NPBWR1MCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463046-A | 1-β-methyl-2-thiolic carbapenem derivatives | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1995-10-31 | — | — | US | disclosed |