Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 13/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443388 | 0.97 | ACHE (0.46) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL8530216 | 0.91 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL8987290 | 0.82 | LMNA (0.40) | NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8987469 | 0.82 | LMNA (0.40) | NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6141279 | 0.77 | ACE2 (0.38) | LMNAEPHX1ACE2 | |
| SCHEMBL8441647 | 0.77 | ACE2 (0.38) | LMNAEPHX1ACE2 | |
| SCHEMBL30517777 | 0.76 | MEN1 (0.41) | LMNAACE2 | |
| SCHEMBL10893886 | 0.75 | ACHE (0.49) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL8533291 | 0.74 | CYP3A4 (0.48) | LMNA | |
| SCHEMBL5720257 | 0.74 | ACE2 (0.35) | LMNAEPHX1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905165-A | Alkyl N-(hydroxyalkyl) carbamates and their application in cosmetics, more particularly in hair compositions | L'OREAL (FR) | 1999-05-18 | — | — | US | claimed |
| US-5788992-A | COSMETICS AND HAIR CONDITIONERS | L'OREAL (FR) | 1998-08-04 | — | — | US | claimed |
| EP-0666251-B1 | N-hydroxy substituted alkyl carbamates and their use in cosmetics especially in hair-care compositions | OREAL (FR) | 1996-12-04 | — | — | EP | claimed |
| US-5905165-A | Alkyl N-(hydroxyalkyl) carbamates and their application in cosmetics, more particularly in hair compositions | L'OREAL (FR) | 1999-05-18 | — | — | US | disclosed |
| US-5788992-A | COSMETICS AND HAIR CONDITIONERS | L'OREAL (FR) | 1998-08-04 | — | — | US | disclosed |
| EP-0677288-B1 | Cosmetic or pharmaceutic composition comprising an alkyl-carbamate as moisturizing agent | OREAL (FR) | 1998-01-28 | — | — | EP | disclosed |
| EP-0677288-A1 | Cosmetic or pharmaceutic composition comprising an alkyl-carbonate as moisturizing agent | L'OREAL (FR) | 1995-10-18 | — | — | EP | disclosed |