Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 12/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440800 | 0.91 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ACHELMNA | |
| SCHEMBL8443388 | 0.91 | ACHE (0.46) | NPC1RAB9ASMN1; SMN2ACHEHRH4 | |
| SCHEMBL5720416 | 0.76 | CHRNB2 (0.35) | — | |
| SCHEMBL8987469 | 0.75 | LMNA (0.40) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL8987290 | 0.75 | LMNA (0.40) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL8533291 | 0.73 | CYP3A4 (0.48) | HRH4HRH3LMNAKDM4E | |
| SCHEMBL28573510 | 0.71 | ACE2 (0.38) | ACHEHRH4HRH3 | |
| SCHEMBL28577151 | 0.71 | ACE2 (0.38) | ACHEHRH4HRH3 | |
| SCHEMBL28418967 | 0.70 | TSHR (0.44) | ACHEHRH4HRH3 | |
| SCHEMBL1301841 | 0.69 | ALDH1A1 (0.52) | RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849308-A | Method of providing surfactant properties to a cosmetic or pharmaceutical composition using alkyl N-(hydroxyalkyl) carbamates | L'OREAL (FR) | 1998-12-15 | — | — | US | disclosed |