Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | PDE1A | P54750 | 2/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083014 | 0.81 | CA12 (0.39) | ALDH1A1TDP1CYP11B1CYP11B2PDE1A | |
| SCHEMBL1083035 | 0.81 | GABRA1 (0.43) | ALDH1A1TDP1CYP1A2CYP3A4GABRA1 | |
| Hydrochloric Acid SCHEMBL1083637 | 0.80 | MAPK1 (0.39) | ALDH1A1TDP1CYP11B1CYP11B2PDE1A | |
| SCHEMBL1752323 | 0.72 | GPR35 (0.40) | ALDH1A1TDP1CYP1A2CYP3A4GABRA1 | |
| SCHEMBL28187985 | 0.69 | ALDH1A1 (0.48) | ALDH1A1TDP1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL1447305 | 0.69 | HTT (0.38) | ALDH1A1LMNA | |
| SCHEMBL3824873 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TDP1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL3824877 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TDP1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL28191486 | 0.68 | ALDH1A1 (0.46) | ALDH1A1TDP1NPSR1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL6516189 | 0.68 | ALDH1A1 (0.49) | ALDH1A1TDP1NPSR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700679-B1 | Injectable liposomal compositions | BAYER AG (DE) | 1999-12-08 | — | — | EP | disclosed |
| US-5653998-A | Injectable liposomal pharmaceutical preparations | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-05 | — | — | US | disclosed |
| EP-0700679-A1 | Injectable liposomal compositions | BAYER AG (DE) | 1996-03-13 | — | — | EP | disclosed |