Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858643 | 1.00 | TRPM8 (0.41) | TRPM8TP53SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL7662323 | 0.91 | TRPM8 (0.39) | TRPM8TP53SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL7662318 | 0.91 | TRPM8 (0.39) | TRPM8TP53SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL7653811 | 0.75 | CHRNB2 (0.41) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7653817 | 0.75 | CHRNB2 (0.41) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8403381 | 0.74 | IDO1 (0.42) | — | |
| SCHEMBL8403377 | 0.74 | IDO1 (0.42) | — | |
| SCHEMBL3084308 | 0.74 | ALDH1A1 (0.50) | TRPM8TP53SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL8442964 | 0.74 | SMN1; SMN2 (0.43) | TRPM8TP53SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL8639304 | 0.73 | KDM4E (0.47) | TP53SMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606251-B1 | FUNGICIDES | ZENECA LTD (GB) | 1997-01-08 | — | — | EP | disclosed |
| EP-0711751-A1 | Process for the preparation of intermediates for oxime ether- or 2-phenyl-3-methyl propenoate-fungicides | ZENECA LIMITED (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1993007116-A1 | FUNGICIDES | ZENECA LIMITED (GB) | 1993-04-15 | — | — | WO | disclosed |