Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.46 |
| ▸ | PPARA | Q07869 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936429 | 0.78 | LTB4R (0.45) | PPARGPPARAMEN1KMT2AKDM4E | |
| SCHEMBL9374602 | 0.74 | GSK3B (0.50) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL8440090 | 0.73 | PPARG (0.44) | PPARGPPARACYP1A2MAPTCYP2C9 | |
| SCHEMBL8892290 | 0.72 | PPARG (0.41) | PPARGPPARACYP1A2MAPTCYP2C9 | |
| SCHEMBL1024088 | 0.71 | HTT (0.62) | PPARGPPARAMEN1KMT2AALDH1A1 | |
| SCHEMBL1023633 | 0.71 | PPARG (0.46) | PPARGPPARAMEN1KMT2AKDM4E | |
| SCHEMBL28048633 | 0.70 | ALDH1A1 (0.50) | PPARGPPARAMEN1KMT2AKDM4E | |
| SCHEMBL8442352 | 0.70 | PRKCI (0.37) | PPARGPPARAMEN1KMT2ATSHR | |
| SCHEMBL6136991 | 0.69 | LTB4R (0.44) | PPARGPPARASMN1; SMN2 | |
| SCHEMBL6935194 | 0.69 | LTB4R (0.46) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | disclosed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |