Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440427 | 0.81 | HTR1A (0.43) | HTR1AOPRL1KDM4EGMNNALDH1A1 | |
| SCHEMBL8440322 | 0.77 | HTR1A (0.56) | HTR1ASLC6A4 | |
| SCHEMBL6972154 | 0.72 | HTR1A (1.00) | HTR1AOPRL1 | |
| SCHEMBL8443416 | 0.70 | HTR1A (0.35) | HTR1A | |
| SCHEMBL8443740 | 0.65 | HTR1A (0.52) | HTR1AALDH1A1LMNACYP3A4MAPK1 | |
| SCHEMBL8441075 | 0.64 | HTR1A (0.57) | HTR1AHTR2A | |
| SCHEMBL23987301 | 0.60 | HTR1A (0.39) | HTR1ASLC6A4 | |
| SCHEMBL8439326 | 0.60 | HTR1A (0.58) | HTR1AOPRL1SLC6A4 | |
| SCHEMBL8439359 | 0.58 | HTR1A (0.55) | HTR1AALDH1A1LMNACYP3A4HTR2A | |
| SCHEMBL8439626 | 0.58 | HTR1A (0.57) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958927-A | PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-09-28 | — | — | US | disclosed |