SCHEMBL8445221

SCHEMBL8445221

CCCCN1CCC(=O)C1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
THRB P10828 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
HPGD P15428 1/20 0.50
SIGMAR1 Q99720 5/20 0.43
DRD3 P35462 4/20 0.43
DRD2 P14416 3/20 0.43
ABCB1 P08183 1/20 0.42
HTR1A P08908 1/20 0.40
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
DRD4 P21917 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7715035 0.94 ABCB1 (0.49) ALDH1A1THRBL3MBTL1HPGDSIGMAR1
SCHEMBL21047883 0.92 HTR1A (0.48) ALDH1A1THRBL3MBTL1HPGDABCB1
SCHEMBL21047565 0.92 HTR1A (0.48) ALDH1A1THRBL3MBTL1HPGDABCB1
SCHEMBL21047906 0.92 HTR1A (0.48) ALDH1A1THRBL3MBTL1HPGDABCB1
SCHEMBL21047618 0.92 HTR1A (0.48) ALDH1A1THRBL3MBTL1HPGDABCB1
SCHEMBL1732235 0.92 HTR1A (0.48) ALDH1A1THRBL3MBTL1HPGDABCB1
SCHEMBL4661561 0.89 ALDH1A1 (0.43) ALDH1A1THRBL3MBTL1HPGDSIGMAR1
SCHEMBL3734236 0.88 ALDH1A1 (0.44) ALDH1A1THRBL3MBTL1HPGDSIGMAR1
SCHEMBL8108347 0.87 ALDH1A1 (0.45) ALDH1A1THRBL3MBTL1HPGDSIGMAR1
SCHEMBL4446353 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449989-A1 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES Sloan-Kettering Institute For Cancer Research (US) 1991-10-09 EP claimed
WO-1990007496-A1 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1990-07-12 WO claimed
US-20260055296-A1 A COATING COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 2026-02-26 US disclosed
US-20250326949-A1 A COATING COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 2025-10-23 US disclosed
EP-4441122-A1 A COATING COMPOSITION PPG Industries Ohio Inc. (US) 2024-10-09 EP disclosed
EP-4441115-A1 A COATING COMPOSITION PPG Industries Ohio Inc. (US) 2024-10-09 EP disclosed
CN-118679202-A Coating composition PPG工业俄亥俄公司 2024-09-20 CN disclosed
CN-118339214-A Coating composition PPG工业俄亥俄公司 2024-07-12 CN disclosed
WO-2023102360-A1 A COATING COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 2023-06-08 WO disclosed
WO-2023102361-A1 A COATING COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 2023-06-08 WO disclosed
EP-3495341-B1 PREPARATION PROCESS OF PERFLUOROALKYL COMPOUND WITH MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL KANTO DENKA KOGYO KK (JP) 2022-11-02 EP disclosed
EP-3495341-A1 METHOD FOR PRODUCING PERFLUOROALKYL COMPOUND USING MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL Kanto Denka Kogyo Co., Ltd. (JP) 2019-06-12 EP disclosed
US-20190169107-A1 PREPARATION PROCESS OF PERFLUOROALKYL COMPOUND WITH MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) 2019-06-06 US disclosed
CN-109563016-A Using single hydrogen perfluoro alkane as the manufacturing method of the all-fluoroalkyl compound of starting material 关东电化工业株式会社 2019-04-02 CN disclosed
EP-0934080-A2 1,3-BIS-(N-LACTAMYL) PROPANE AND THE PHARMACEUTICAL AND COSMETIC USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1999-08-11 EP disclosed
WO-1998015291-A1 1,3-BIS-(N-LACTAMYL) PROPANE AND THE PHARMACEUTICAL AND COSMETIC USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1998-04-16 WO disclosed
EP-0449989-A1 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES Sloan-Kettering Institute For Cancer Research (US) 1991-10-09 EP disclosed
WO-1990007496-A1 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1990-07-12 WO disclosed
US-4925939-A 6,7-dihydropyrrol[3,4-c]pyrido[2,3-d]pyrimidine derivatives SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1990-05-15 US disclosed
US-4005208-A GASTRIC JUICE, ANTISECRETORY SMITHKLINE CORPORATION (US) 1977-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190169107-A1 PREPARATION PROCESS OF PERFLUOROALKYL COMPOUND WITH MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL PFKFB1, PFKFB4, PFAS ALDH1A1 505/4885THRB 2143/4885L3MBTL1 4323/4885
US-20260055296-A1 A COATING COMPOSITION PUF60, PELI1, COPE ALDH1A1 170/4885THRB 3134/4885L3MBTL1 4252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.