Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789823 | 0.87 | ADAMTS4 (0.54) | ADAMTS4MMP13MMP1MMP2MMP3 | |
| SCHEMBL28849866 | 0.85 | ADAMTS4 (0.51) | ADAMTS4TDP1MMP13MMP1MMP2 | |
| SCHEMBL1185524 | 0.84 | MMP2 (0.50) | ADAMTS4MMP13MMP1MMP2MMP3 | |
| SCHEMBL27465878 | 0.84 | ALDH1A1 (0.50) | ADAMTS4TDP1MMP13MMP1MMP2 | |
| SCHEMBL8445730 | 0.84 | MMP2 (0.59) | ADAMTS4MMP13MMP1MMP2MMP3 | |
| SCHEMBL1186251 | 0.84 | MMP2 (0.50) | ADAMTS4MMP13MMP1MMP2MMP3 | |
| SCHEMBL29540524 | 0.83 | HSD17B10 (0.54) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL6796513 | 0.82 | MMP13 (0.50) | ADAMTS4MMP13MMP1MMP2MMP3 | |
| SCHEMBL7669662 | 0.81 | MMP9 (0.62) | MMP2MMP9L3MBTL1KMT2AMEN1 | |
| SCHEMBL7692231 | 0.81 | TDP1 (0.49) | ADAMTS4TDP1MMP13MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177466-B1 | Sulfonylamino acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-01-23 | — | — | US | disclosed |