Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 4/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP7 | P09237 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796513 | 0.88 | MMP13 (0.50) | ADAMTS4ALDH1A1HSD17B10L3MBTL1ALOX5AP | |
| SCHEMBL7897307 | 0.87 | ADAMTS4 (0.47) | ADAMTS4ALDH1A1HSD17B10L3MBTL1HPGD | |
| SCHEMBL27465878 | 0.85 | ALDH1A1 (0.50) | ADAMTS4ALDH1A1HSD17B10L3MBTL1ALOX5AP | |
| SCHEMBL1185524 | 0.85 | MMP2 (0.50) | ADAMTS4ALDH1A1MMP9MMP2MMP3 | |
| SCHEMBL8445730 | 0.85 | MMP2 (0.59) | ADAMTS4ALDH1A1ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL14419201 | 0.85 | MMP9 (0.56) | ADAMTS4MMP9MMP2MMP3MMP13 | |
| SCHEMBL1186251 | 0.85 | MMP2 (0.50) | ADAMTS4ALDH1A1MMP9MMP2MMP3 | |
| SCHEMBL7669662 | 0.85 | MMP9 (0.62) | ALDH1A1HSD17B10L3MBTL1HPGDLMNA | |
| SCHEMBL29540524 | 0.84 | HSD17B10 (0.54) | ALDH1A1HSD17B10L3MBTL1HPGDPOLB | |
| SCHEMBL11578980 | 0.84 | ADAMTS4 (0.59) | ADAMTS4ALDH1A1HSD17B10L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2008036294-A2 | NOS INHIBITORS FOR TREATMENT OF MOTOR DEFICIT DISORDERS | NORTHWESTERN UNIVERSITY (US) | 2008-03-27 | — | — | WO | disclosed |