Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 7/20 | 0.44 |
| ▸ | MMP2 | P08253 | 7/20 | 0.44 |
| ▸ | MMP13 | P45452 | 7/20 | 0.44 |
| ▸ | MMP8 | P22894 | 6/20 | 0.44 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448761 | 0.94 | MMP9 (0.46) | MMP9MMP2MMP13MMP8BMP1 | |
| SCHEMBL8445867 | 0.87 | MMP2 (0.48) | MMP9MMP2MMP13MMP8BMP1 | |
| SCHEMBL8451686 | 0.84 | MMP9 (0.45) | MMP9MMP2MMP13MMP8BMP1 | |
| SCHEMBL8446552 | 0.84 | MMP9 (0.42) | MMP9MMP2MMP13MMP8BMP1 | |
| SCHEMBL8446566 | 0.82 | MMP2 (0.51) | MMP9MMP2MMP13MMP8BMP1 | |
| SCHEMBL8446283 | 0.81 | MMP9 (0.47) | MMP9MMP2MMP13MMP8MMP3 | |
| SCHEMBL8451051 | 0.81 | POLB (0.41) | MMP9MMP2MMP13MMP8MMP3 | |
| SCHEMBL8448395 | 0.81 | ALDH1A1 (0.43) | MMP9MMP2MMP13MMP8BMP1 | |
| SCHEMBL8448762 | 0.80 | MMP9 (0.50) | MMP9MMP2MMP13MMP8BMP1 | |
| SCHEMBL8445895 | 0.79 | MMP9 (0.47) | MMP9MMP2MMP13MMP8BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |