Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | BMP1 | P13497 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445867 | 0.93 | MMP2 (0.48) | MMP9MMP2MMP8MMP13BMP1 | |
| SCHEMBL8448761 | 0.86 | MMP9 (0.46) | MMP9MMP2MMP8MMP13BMP1 | |
| SCHEMBL8451690 | 0.85 | BMP1 (0.53) | MMP9MMP2MMP8MMP13BMP1 | |
| SCHEMBL8446555 | 0.85 | BMP1 (0.46) | MMP9MMP2MMP8MMP13BMP1 | |
| SCHEMBL8446567 | 0.83 | BMP1 (0.56) | MMP9MMP2MMP8MMP13BMP1 | |
| SCHEMBL8451054 | 0.82 | BMP1 (0.46) | MMP9MMP2MMP8MMP13BMP1 | |
| SCHEMBL8448399 | 0.82 | BMP1 (0.55) | MMP9MMP2MMP8MMP13BMP1 | |
| SCHEMBL8446284 | 0.82 | MMP9 (0.59) | MMP9MMP2MMP8MMP13BMP1 | |
| Hydrochloric Acid SCHEMBL8445776 | 0.81 | MMP2 (0.54) | MMP9MMP2MMP8MMP13BMP1 | |
| Hydrochloric Acid SCHEMBL8448226 | 0.81 | BMP1 (0.54) | MMP9MMP2MMP8MMP13BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |