Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.55 |
| ▸ | DOT1L | Q8TEK3 | 6/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.54 |
| ▸ | NSD2 | O96028 | 3/20 | 0.54 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.54 |
| ▸ | TRDMT1 | O14717 | 3/20 | 0.54 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.54 |
| ▸ | PCMT1 | P22061 | 2/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.54 |
| ▸ | INMT | O95050 | 2/20 | 0.54 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.54 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.54 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.54 |
| ▸ | RNMT | O43148 | 2/20 | 0.54 |
| ▸ | TPMT | P51580 | 1/20 | 0.54 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.54 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.54 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.54 |
| ▸ | FASN | P49327 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Inosine SCHEMBL8446027 | 1.00 | NNMT (0.55) | NNMTDOT1LCARM1NSD2SETD7 | |
| Adenosine SCHEMBL8013455 | 0.88 | NNMT (0.70) | NNMTDOT1LCARM1NSD2SETD7 | |
| Adenosine SCHEMBL8013453 | 0.88 | NNMT (0.70) | NNMTDOT1LCARM1NSD2SETD7 | |
| Adenosine SCHEMBL6408986 | 0.84 | NNMT (0.76) | NNMTDOT1LCARM1NSD2SETD7 | |
| Adenosine SCHEMBL6408967 | 0.84 | NNMT (0.76) | NNMTDOT1LCARM1NSD2SETD7 | |
| SCHEMBL8446029 | 0.81 | MARS1 (0.51) | NNMTDOT1LCARM1NSD2SETD7 | |
| SCHEMBL855679 | 0.80 | SLC29A1 (0.61) | MAPTADORA3MAPK1ADORA2AADORA2B | |
| Inosine SCHEMBL18048494 | 0.78 | SLC29A1 (0.67) | DOT1LKMT2ADPP4MEN1SLC28A1 | |
| Inosine SCHEMBL330178 | 0.78 | SLC29A1 (0.75) | DOT1LKMT2ADPP4MEN1SLC28A1 | |
| Inosine SCHEMBL20138477 | 0.78 | SLC29A1 (0.75) | DOT1LKMT2ADPP4MEN1SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824345-A4 | S-ADENOSYL METHIONINE REGULATION OF METABOLIC PATHWAYS AND ITS USE IN DIAGNOSIS AND THERAPY | ORIDIGM CORP (US) | 1999-08-25 | — | — | EP | disclosed |
| EP-0824345-A1 | S-ADENOSYL METHIONINE REGULATION OF METABOLIC PATHWAYS AND ITS USE IN DIAGNOSIS AND THERAPY | ORIDIGM CORPORATION (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996033703-A2 | S-ADENOSYL METHIONINE REGULATION OF METABOLIC PATHWAYS AND ITS USE IN DIAGNOSIS AND THERAPY | ORIDIGM CORPORATION (US) | 1996-10-31 | — | — | WO | disclosed |