Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446802 | 0.94 | ALDH1A1 (0.55) | ALDH1A1POLBCNR1CNR2KDM4E | |
| SCHEMBL8447174 | 0.88 | L3MBTL1 (0.46) | ALDH1A1POLBCNR1CNR2KDM4E | |
| SCHEMBL8949435 | 0.87 | HDAC1 (0.45) | ALDH1A1POLBCNR1CNR2KDM4E | |
| SCHEMBL8949485 | 0.87 | NPC1 (0.43) | ALDH1A1POLBCNR1CNR2KDM4E | |
| SCHEMBL27920436 | 0.85 | EPHX2 (0.55) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8949311 | 0.85 | NPC1 (0.44) | ALDH1A1POLBCNR1CNR2HPGD | |
| SCHEMBL27327646 | 0.84 | HDAC1 (0.40) | ALDH1A1POLBCNR1CNR2KDM4E | |
| Hydrochloric Acid SCHEMBL29058723 | 0.84 | EPHX2 (0.54) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8949430 | 0.81 | POLB (0.44) | ALDH1A1POLBCNR1CNR2KDM4E | |
| SCHEMBL8443619 | 0.81 | L3MBTL1 (0.49) | ALDH1A1POLBCNR1CNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |