Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949311 | 0.90 | NPC1 (0.44) | POLBL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL8447174 | 0.90 | L3MBTL1 (0.46) | POLBL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL8949485 | 0.89 | NPC1 (0.43) | POLBL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL8743677 | 0.86 | POLB (0.46) | POLBL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL8446802 | 0.84 | ALDH1A1 (0.55) | POLBL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL8443619 | 0.83 | L3MBTL1 (0.49) | POLBL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL8446189 | 0.81 | ALDH1A1 (0.50) | POLBL3MBTL1NPC1SMN1; SMN2CNR1 | |
| SCHEMBL8949435 | 0.80 | HDAC1 (0.45) | POLBL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL23886143 | 0.78 | TP53 (0.51) | POLBL3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8390808 | 0.77 | POLB (0.50) | POLBL3MBTL1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1037511-C | Therapeutic agents | BOOTS CO PLC (GB) | 1998-02-25 | — | — | CN | disclosed |
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |