Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446802 | 0.90 | ALDH1A1 (0.55) | L3MBTL1CNR1CNR2POLBMEN1 | |
| SCHEMBL8949430 | 0.90 | POLB (0.44) | L3MBTL1CNR1CNR2POLBMEN1 | |
| SCHEMBL8446189 | 0.88 | ALDH1A1 (0.50) | L3MBTL1CNR1CNR2POLBGAA | |
| SCHEMBL8443619 | 0.86 | L3MBTL1 (0.49) | L3MBTL1CNR1CNR2POLBMEN1 | |
| SCHEMBL8949311 | 0.84 | NPC1 (0.44) | L3MBTL1CNR1CNR2POLBMEN1 | |
| SCHEMBL30166184 | 0.83 | HPGD (0.50) | CNR1CNR2GAAMEN1KMT2A | |
| SCHEMBL8743677 | 0.83 | POLB (0.46) | L3MBTL1CNR1CNR2POLBMEN1 | |
| SCHEMBL1829561 | 0.83 | ALOX5 (0.50) | L3MBTL1CNR1CNR2GAAALDH1A1 | |
| SCHEMBL8949485 | 0.83 | NPC1 (0.43) | L3MBTL1CNR1CNR2POLBMEN1 | |
| SCHEMBL8949435 | 0.80 | HDAC1 (0.45) | L3MBTL1CNR1CNR2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |