Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 7/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8068549 | 0.99 | MRGPRX1 (0.34) | MRGPRX1GCKROCK2ALDH1A1LMNA | |
| SCHEMBL8447163 | 0.87 | NPSR1 (0.41) | GCKALDH1A1LMNAMMP9 | |
| Hydrochloric Acid SCHEMBL8445988 | 0.85 | L3MBTL1 (0.37) | MRGPRX1GCKLMNAMCL1F10 | |
| SCHEMBL8446233 | 0.82 | MAPT (0.36) | MRGPRX1ALDH1A1LMNAF10 | |
| Hydrochloric Acid SCHEMBL8068552 | 0.81 | MAPT (0.35) | MRGPRX1ALDH1A1LMNAF10 | |
| SCHEMBL8444240 | 0.79 | MRGPRX1 (0.37) | MRGPRX1ALDH1A1LMNAMCL1F10 | |
| Hydrochloric Acid SCHEMBL8070680 | 0.78 | MRGPRX1 (0.36) | MRGPRX1ALDH1A1LMNAMCL1F10 | |
| SCHEMBL8068683 | 0.78 | SMN1; SMN2 (0.41) | MRGPRX1GCKLMNAF10 | |
| SCHEMBL8446348 | 0.78 | CA2 (0.43) | MRGPRX1ALDH1A1F10 | |
| Hydrochloric Acid SCHEMBL8059609 | 0.77 | SMN1; SMN2 (0.40) | MRGPRX1GCKLMNAF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | claimed |