Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.45 |
| ▸ | ACE | P12821 | 5/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453054 | 0.88 | MME (0.42) | MMEACECTSBKDM4EALDH1A1 | |
| SCHEMBL8449476 | 0.85 | CTSB (0.45) | MMEACEEPHX2CTSBCASP1 | |
| SCHEMBL8450247 | 0.84 | MME (0.47) | MMEACECTSBECE1ACE2 | |
| SCHEMBL7572242 | 0.84 | MME (0.66) | MMEACECASP1KDM4EALDH1A1 | |
| SCHEMBL7572248 | 0.84 | MME (0.66) | MMEACECASP1KDM4EALDH1A1 | |
| SCHEMBL8453092 | 0.84 | MME (0.43) | MMEACECTSBECE1ACE2 | |
| SCHEMBL8450113 | 0.83 | MME (0.43) | MMEACECTSB | |
| SCHEMBL8446385 | 0.82 | MME (0.60) | MMEACECTSBCASP1KDM4E | |
| SCHEMBL7568408 | 0.81 | MME (0.52) | MMEACEKMT2AACE2 | |
| SCHEMBL7568400 | 0.81 | MME (0.52) | MMEACEKMT2AACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |