Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 7/20 | 0.44 |
| ▸ | ACE | P12821 | 5/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447081 | 0.87 | PPARG (0.42) | CTSBMMEACECASP1PTPN1 | |
| SCHEMBL8446387 | 0.85 | MME (0.45) | CTSBMMEACECASP1OPRM1 | |
| SCHEMBL8453149 | 0.84 | MME (0.47) | CTSBMMEACECASP1PTPN1 | |
| SCHEMBL8451198 | 0.83 | MME (0.48) | CTSBMMEACEECE1 | |
| SCHEMBL8450121 | 0.82 | CTSB (0.45) | CTSBMMEACECCKBR | |
| SCHEMBL7567320 | 0.82 | MME (0.66) | CTSBMMEACECASP1 | |
| SCHEMBL8450108 | 0.81 | MME (0.45) | CTSBMMEACECASP1PTPN1 | |
| SCHEMBL7567288 | 0.79 | MME (0.53) | CTSBMMEACEPTPN1 | |
| SCHEMBL8449475 | 0.79 | MME (0.60) | CTSBMMEACECASP1 | |
| SCHEMBL8447079 | 0.78 | MME (0.46) | CTSBMMEACEPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |