SCHEMBL8453092

CC(C)CN(C[C@H](CCc1ccccc1)C(=O)OCc1ccccc1)C(=O)N[C@@H](C(=O)O)[C@@H](Cc1ccccc1)c1cccc(-c2ccccc2)c1

nearest known ligand 0.43

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MME	P08473	7/20	0.43

▸	ACE	P12821	5/20	0.43

▸	PTGES	O14684	2/20	0.41

▸	CTSB	P07858	1/20	0.39

▸	MMP3	P08254	3/20	0.36

▸	MMP1	P03956	2/20	0.36

▸	ECE1	P42892	2/20	0.36

▸	ACE2	Q9BYF1	1/20	0.35

▸	ITGB3	P05106	1/20	0.35

▸	ITGAV	P06756	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8450247	0.93	MME (0.47)	MMEACECTSBMMP3MMP1
SCHEMBL8450113	0.90	MME (0.43)	MMEACEPTGESCTSBMMP3
SCHEMBL8446495	0.86	MME (0.43)	MMEACEPTGESCTSBMMP3
SCHEMBL8451246	0.86	MME (0.47)	MMEACEPTGESCTSBMMP3
SCHEMBL7573628	0.85	MME (0.55)	MMEACEPTGESACE2ITGB3
SCHEMBL7573635	0.85	MME (0.55)	MMEACEPTGESACE2ITGB3
SCHEMBL8450121	0.85	CTSB (0.45)	MMEACEPTGESCTSBITGB3
SCHEMBL8453054	0.84	MME (0.42)	MMEACECTSBMMP3ECE1
SCHEMBL8453091	0.84	MME (0.48)	MMEACEPTGESCTSBMMP3
SCHEMBL8451272	0.84	PTGES (0.39)	MMEACEPTGESCTSBMMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5968980-A	ENDOPEPTIDASE 24.11 INHIBITORS	SANTEN PHARMACEUTICAL CO., LTD. (JP)	1999-10-19	—	—	US	disclosed