Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 3/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450247 | 0.91 | MME (0.47) | MMEACECPA1ACE2FDFT1 | |
| SCHEMBL8449555 | 0.90 | UTS2R (0.38) | PTGESMMEACECTSBLPAR1 | |
| SCHEMBL8450818 | 0.88 | MME (0.40) | MMEACECPA1ACE2FDFT1 | |
| SCHEMBL7567864 | 0.86 | ACE (0.51) | PTGESMMEACECPA1ACE2 | |
| SCHEMBL7567868 | 0.86 | ACE (0.51) | PTGESMMEACECPA1ACE2 | |
| SCHEMBL8450113 | 0.85 | MME (0.43) | PTGESMMEACECTSBMMP3 | |
| SCHEMBL8451268 | 0.85 | MME (0.46) | PTGESMMEACECPA1ACE2 | |
| SCHEMBL8451246 | 0.84 | MME (0.47) | PTGESMMEACECPA1ACE2 | |
| SCHEMBL8446495 | 0.84 | MME (0.43) | PTGESMMEACECTSBMMP3 | |
| SCHEMBL8453092 | 0.84 | MME (0.43) | PTGESMMEACEACE2CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |