Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | BMP1 | P13497 | 4/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | AOC2 | O75106 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450038 | 0.80 | NPSR1 (0.36) | MMP13BMP1 | |
| SCHEMBL8445750 | 0.75 | MMP9 (0.42) | MMP13 | |
| SCHEMBL8446548 | 0.72 | HAO1 (0.35) | MMP13 | |
| SCHEMBL8450891 | 0.70 | POLB (0.35) | MMP13 | |
| SCHEMBL8450888 | 0.70 | POLB (0.35) | MMP13 | |
| SCHEMBL31219817 | 0.69 | ALDH1A1 (0.42) | MMP13 | |
| SCHEMBL3091945 | 0.65 | MMP2 (0.44) | MMP13BMP1KEAP1NFE2L2 | |
| SCHEMBL6498314 | 0.64 | ADAMTS4 (0.47) | MMP13KEAP1NFE2L2 | |
| SCHEMBL22718351 | 0.64 | NPSR1 (0.37) | BMP1 | |
| SCHEMBL29603329 | 0.64 | NPSR1 (0.37) | BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |