Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 4/20 | 0.56 |
| ▸ | MMP2 | P08253 | 4/20 | 0.55 |
| ▸ | MMP9 | P14780 | 4/20 | 0.55 |
| ▸ | MMP8 | P22894 | 4/20 | 0.55 |
| ▸ | MMP13 | P45452 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445701 | 0.89 | KEAP1 (0.53) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL8446551 | 0.88 | MMP9 (0.59) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL8446566 | 0.87 | MMP2 (0.51) | BMP1MMP2MMP9MMP8MMP13 | |
| Hydrochloric Acid SCHEMBL8445889 | 0.87 | MMP2 (0.58) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL26769912 | 0.84 | HTT (0.59) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL8448762 | 0.83 | MMP9 (0.50) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL8451690 | 0.82 | BMP1 (0.53) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL8445867 | 0.81 | MMP2 (0.48) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL8451054 | 0.81 | BMP1 (0.46) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL7344309 | 0.81 | BMP1 (0.80) | BMP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |