Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GGT1 | P19440 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844727 | 0.92 | KDM4E (0.70) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL11065761 | 0.86 | KDM4E (0.67) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| Diaspirin SCHEMBL40799 | 0.85 | KDM4E (0.75) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| Diaspirin SCHEMBL30735506 | 0.85 | KDM4E (0.75) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL17787232 | 0.84 | KDM4E (0.60) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL12446248 | 0.84 | KDM4E (0.69) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL8436639 | 0.83 | KDM4E (0.63) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL27145067 | 0.83 | KDM4E (0.58) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL6129343 | 0.81 | KDM4E (0.61) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| Bromoaspirin SCHEMBL6691615 | 0.81 | KDM4E (0.61) | KDM4EHSD17B10HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160096788-A1 | LIQUID CRYSTAL COMPOSITION HAVING A NEGATIVE LIQUID CRYSTAL MODE | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-04-07 | — | — | US | claimed |
| US-9011734-B2 | Ligand exchange thermochromic, (LETC), systems | PLEOTINT, L.L.C. (US) | 2015-04-21 | — | — | US | claimed |
| US-8018639-B2 | Ligand exchange thermochromic, (LETC), systems | PLEOTINT, L.L.C. (US) | 2011-09-13 | — | — | US | claimed |
| US-20090283728-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, LLC (US) | 2009-11-19 | — | — | US | claimed |
| EP-2082005-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | Pleotint, L.L.C. (US) | 2009-07-29 | — | — | EP | claimed |
| US-20080100902-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, LLC (US) | 2008-05-01 | — | — | US | claimed |
| WO-2008028128-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, L.L.C. (US) | 2008-03-06 | — | — | WO | claimed |
| US-20160096788-A1 | LIQUID CRYSTAL COMPOSITION HAVING A NEGATIVE LIQUID CRYSTAL MODE | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-04-07 | — | — | US | disclosed |
| EP-2436750-A2 | Ligand exchange thermochromic, (LETC), systems | Pleotint, L.L.C. (US) | 2012-04-04 | — | — | EP | disclosed |
| EP-2434000-A2 | Ligand exchange thermochromic, (LETC), systems | Pleotint, L.L.C. (US) | 2012-03-28 | — | — | EP | disclosed |
| US-7253232-B2 | Thermoplastic compositions with enhanced melt flow and compatibility | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-08-07 | — | — | US | disclosed |
| US-20070064195-A1 | Stabilization of photochromic systems | CIBA CORPORATION | 2007-03-22 | — | — | US | disclosed |
| US-20050288435-A1 | Thermoplastic compositions with enhanced melt flow and compatibility | CIBA SPECIALTY CHEMICALS CORP. | 2005-12-29 | — | — | US | disclosed |
| WO-1999026934-A1 | TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 1999-06-03 | — | — | WO | disclosed |
| WO-1999026935-A1 | TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS | CYTEC TECHNOLOGY CORP. (US) | 1999-06-03 | — | — | WO | disclosed |
| US-5788891-A | Method for the forming of ceramic green parts | CERAMTEC AG INNOVATIVE CERAMIC ENGINEERING (DE) | 1998-08-04 | — | — | US | disclosed |
| US-5449776-A | Polypropylene | CIBA-GEIGY CORPORATION (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0605694-A1 | PROCESS FOR PRODUCING CERAMIC GREEN BODIES. | GAUCKLER LUDWIG J (CH) | 1994-07-13 | — | — | EP | disclosed |
| WO-1994002429-A1 | PROCESS FOR PRODUCING CERAMIC GREEN BODIES | GAUCKLER LUDWIG J (CH) | 1994-02-03 | — | — | WO | disclosed |
| US-4007158-A | 9-AZA- 1,5-DIOXA-SPIRO (5,5) UNDECANES | SANKYO COMPANY LIMITED (JA) | 1977-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160096788-A1 | LIQUID CRYSTAL COMPOSITION HAVING A NEGATIVE LIQUID CRYSTAL MODE | SHBG, NCAPD2, RCC2 | KDM4E 4394/4885HSD17B10 701/4885HPGD 4482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.