Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413362 | 0.87 | TSHR (0.53) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL11202237 | 0.80 | PDE7A (0.49) | HSD17B10L3MBTL1TDP1ALDH1A1PDE7A | |
| SCHEMBL8446725 | 0.78 | TSHR (0.58) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL17498318 | 0.78 | TDP1 (0.62) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL11432656 | 0.78 | ALDH1A1 (0.54) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL18814844 | 0.77 | TSHR (0.49) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL8444659 | 0.76 | HTT (0.53) | ALOX15MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL9815413 | 0.76 | TSHR (0.55) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL8445197 | 0.74 | TSHR (0.53) | ALOX15MAPK1HSD17B10L3MBTL1TSHR | |
| SCHEMBL535242 | 0.74 | ALOX15 (0.74) | ALOX15MAPK1HSD17B10L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656202-B1 | Dyeing composition containing sulphurous p-phenylene-diamines, sulphurous p-phenylenediamines and method of preparation | OREAL (FR) | 1999-05-06 | — | — | EP | claimed |