Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | MMP9 | P14780 | 4/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8448226 | 0.99 | BMP1 (0.54) | BMP1ALDH1A1ACACBMMP2MMP9 | |
| SCHEMBL8446564 | 0.90 | ALDH1A1 (0.46) | BMP1ALDH1A1ACACBMMP2MMP9 | |
| SCHEMBL8446547 | 0.90 | BMP1 (0.47) | BMP1ALDH1A1ACACBSMN1; SMN2NR4A1 | |
| SCHEMBL8448395 | 0.89 | ALDH1A1 (0.43) | BMP1ALDH1A1ACACBMMP2MMP9 | |
| SCHEMBL8448762 | 0.82 | MMP9 (0.50) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL8445867 | 0.80 | MMP2 (0.48) | BMP1MMP2MMP9MMP8MMP13 | |
| Hydrochloric Acid SCHEMBL8445776 | 0.79 | MMP2 (0.54) | BMP1ACACBMMP2MMP9MMP8 | |
| SCHEMBL8451690 | 0.77 | BMP1 (0.53) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL8446555 | 0.77 | BMP1 (0.46) | BMP1MMP2MMP9MMP8MMP13 | |
| SCHEMBL8446551 | 0.76 | MMP9 (0.59) | BMP1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |