Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.63 |
| ▸ | MMP9 | P14780 | 7/20 | 0.60 |
| ▸ | MMP2 | P08253 | 7/20 | 0.60 |
| ▸ | MMP13 | P45452 | 7/20 | 0.60 |
| ▸ | MMP3 | P08254 | 6/20 | 0.60 |
| ▸ | MMP1 | P03956 | 5/20 | 0.60 |
| ▸ | MMP7 | P09237 | 5/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446541 | 0.85 | MMP1 (0.60) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL12467072 | 0.84 | MMP9 (0.58) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL254532 | 0.84 | MMP9 (0.58) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8446616 | 0.83 | ADAMTS4 (0.61) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8450205 | 0.82 | MMP9 (0.75) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8449004 | 0.82 | MMP9 (0.75) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL8283901 | 0.81 | MMP2 (0.76) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL4975578 | 0.80 | ADAMTS4 (0.71) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL698908 | 0.80 | ADAMTS4 (0.71) | ADAMTS4MMP9MMP2MMP13MMP3 | |
| SCHEMBL698907 | 0.80 | ADAMTS4 (0.71) | ADAMTS4MMP9MMP2MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |