Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | NR1D2 | Q14995 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444887 | 0.88 | NR1D1 (0.50) | NR1D1ALDH1A1MAPTLMNACCR5 | |
| SCHEMBL8522244 | 0.88 | NR1D1 (0.51) | NR1D1ALDH1A1MAPTLMNANR1H3 | |
| SCHEMBL7463392 | 0.88 | NR1D1 (0.51) | NR1D1ALDH1A1MAPTLMNANR1H3 | |
| SCHEMBL7463372 | 0.79 | ALDH1A1 (0.47) | NR1D1ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL8449180 | 0.79 | ALDH1A1 (0.47) | NR1D1ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL8449163 | 0.79 | ALDH1A1 (0.44) | NR1D1ALDH1A1MAPTLMNA | |
| SCHEMBL8444914 | 0.77 | GRIN2B (0.37) | ALDH1A1MAPTCCR5GRIN2B | |
| SCHEMBL8448648 | 0.77 | GRIN2B (0.37) | ALDH1A1MAPTCCR5GRIN2B | |
| SCHEMBL7449786 | 0.77 | ALDH1A1 (0.41) | NR1D1ALDH1A1MAPTLMNACCR5 | |
| Sulfuric Acid SCHEMBL5897764 | 0.76 | CCR5 (0.39) | NR1D1ALDH1A1MAPTLMNACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977097-A | 1-methylcarbapenem derivatives | SANKYO COMPANY LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |