Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449786 | 0.87 | ALDH1A1 (0.41) | CCR5ALDH1A1LMNAMAPTNR1D1 | |
| Sulfuric Acid SCHEMBL5897763 | 0.81 | CCR2 (0.40) | CCR5ALDH1A1LMNAMAPTUSP30 | |
| SCHEMBL5669278 | 0.80 | SIGMAR1 (0.35) | CCR5ALDH1A1LMNASIGMAR1 | |
| SCHEMBL5669431 | 0.80 | CCR5 (0.34) | CCR5ALDH1A1LMNASIGMAR1 | |
| SCHEMBL7462454 | 0.78 | SIGMAR1 (0.41) | CCR5ALDH1A1LMNAMAPTSIGMAR1 | |
| SCHEMBL7449775 | 0.78 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTNR1D1USP30 | |
| SCHEMBL7458615 | 0.77 | CCR2 (0.41) | ALDH1A1LMNAMAPTNR1D1USP30 | |
| SCHEMBL8449134 | 0.76 | NR1D1 (0.49) | CCR5ALDH1A1LMNAMAPTNR1D1 | |
| SCHEMBL8094828 | 0.76 | ALDH1A1 (0.45) | CCR5ALDH1A1LMNAMAPTNR1D1 | |
| SCHEMBL7456013 | 0.76 | SIGMAR1 (0.40) | CCR5ALDH1A1LMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091363-B2 | Compounds for the preparation of carbapenem-type antibacterial agents | SANKYO COMPANY, LIMITED (JP) | 2006-08-15 | — | — | US | disclosed |
| US-7034150-B2 | Processes for the preparation of carbapenem-type antibacterial agents | SANKYO COMPANY, LIMITED (JP) | 2006-04-25 | — | — | US | disclosed |
| US-20060009508-A1 | Compounds for the preparation of carbapenem-type antibacterial agents | SANKYO COMPANY, LIMITED (JP) | 2006-01-12 | — | — | US | disclosed |
| US-20030225055-A1 | Processes for the preparation of carbapenem-type antibacterial agents | SANKYO COMPANY, LIMITED (JP) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225055-A1 | Processes for the preparation of carbapenem-type antibacterial agents | OXA1L, MRPL21, IRAK1 | CCR5 931/4885ALDH1A1 1903/4885LMNA 740/4885 |
| US-20060009508-A1 | Compounds for the preparation of carbapenem-type antibacterial agents | TET1, MRPL21, RPS6KA1 | CCR5 1830/4885ALDH1A1 2722/4885LMNA 589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.